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Content body: Cancer spread (metastasis) occurs when small pieces of the primary tumour break off and invade distant tissues. This is why metastatic breast cancers are particularly hard to treat, not only because they are found at multiple sites in the body, but also because they may contain more genetic mutations than the original tumour itself. Researchers from the University of North Carolina Lineberger Comprehensive Cancer Center came to this conclusion by studying patient samples, and they suspect that these genetic differences might explain why not all breast tumours can be treated the same. Learn more in an article from UNC Lineberger.