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Treatments for stage 3 stomach cancer
The following are treatment options for stage 3 stomach cancer. Your healthcare team will suggest treatments based on your needs and work with you to develop a treatment plan.
Surgery
Surgery is one of the main treatments for stage 3 stomach cancer.
Gastrectomy
A gastrectomy to remove all or part of the stomach is the most common type of surgery to treat stage 3 cancer.
Lymph node dissection
A lymph node dissection is done to remove lymph nodes around the stomach for stage 3 stomach cancer.
Chemotherapy
Chemotherapy is a main treatment for stage 3 stomach cancer. Chemotherapy may be given before (neoadjuvant therapy) or after surgery (adjuvant therapy) or both before and after surgery (perioperative chemotherapy). It may also be given over the same time period as radiation therapy (called chemoradiation). The most common combinations of chemotherapy drugs given for stage 3 stomach cancer are:
- 5-fluorouracil (Adrucil, 5-FU) and leucovorin (folonic acid)
- ECF – epirubicin (Pharmorubicin), cisplatin (Platinol AQ) and 5-fluorouracil
- ECX – epirubicin, cisplatin and capecitabine (Xeloda)
- cisplatin and 5-fluorouracil
- paclitaxel (Taxol) and carboplatin (Paraplatin)
Chemoradiation
Radiation therapy may be offered for stage 3 stomach cancer along with chemotherapy. The type of radiation therapy used most often is external beam radiation therapy.
Clinical trials
You may be asked if you want to join a clinical trial for stomach cancer. Find out more about clinical trials.
How can you stop cancer before it starts?

Discover how 16 factors affect your cancer risk and how you can take action with our interactive tool – It’s My Life! Presented in partnership with Desjardins.