Lung cancer

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The lungs

The lungs are part of your respiratory system, the group of organs and tissues involved in breathing. You have 2 lungs, and they take up most of the space inside your chest.

The windpipe (trachea) is a tube-shaped airway that leads to the lungs through the neck and chest. The windpipe further divides into 2 tubes that are the main airway to each lung. These airway tubes are called bronchi and they branch out into smaller and smaller tubes.

The lungs are separated by the mediastinum, which contains the heart and other organs. Below the lungs is the diaphragm, a thin muscle that separates the chest cavity from the abdomen.

The lungs are surrounded by the chest wall. The chest wall is made up of the ribs and the muscles between the ribs.

Structure

Each lung is divided into lobes (sections):

  • The right lung has 3 lobes and is slightly larger than the left lung.
  • The left lung has 2 lobes. The heart sits in the cardiac notch, which is a groove in the lower lobe.

Graphic of the structure of the lungs

Parts of the lung

The 2 main bronchi divide or branch into smaller bronchi, tubes which have small glands and cartilage in their walls. These smaller bronchi eventually divide into even smaller tubes called bronchioles, which have no glands or cartilage. At the end of the bronchioles are millions of tiny air sacs called alveoli. Surrounding the alveoli are very tiny blood vessels (called capillaries).

The bronchi are lined with cells that have very fine hair-like projections called cilia.

Each lung is covered by a thin membrane called the pleura. The pleura also lines the inner side of the rib cage. It protects and cushions the lungs and produces a fluid that acts like a lubricant so the lungs can move smoothly in the chest cavity. The pleura is made up of 2 layers:

  • inner (visceral) pleura – the layer next to the lung
  • outer (parietal) pleura – the layer that lines the chest wall

The area between the 2 layers of the pleura is called the pleural space.

The lymphatic system of the lung

Different groups of lymph nodes, which are part of the lymphatic system, drain fluid that the lungs produce. These groups of lymph nodes are:

  • bronchial nodes – lymph nodes in the lung around the ends of the bronchi
  • hilar nodes – lymph nodes in the area where the windpipe divides into the main bronchi
  • mediastinal nodes – lymph nodes along the windpipe in between the 2 lungs
  • subcarinal nodes – lymph nodes just below the windpipe where it divides into the main bronchi

Graphic of the lymph nodes around the lung.

What the lungs do

The main functions of the lungs are to transfer oxygen from the air to the blood and to release carbon dioxide from the blood to the air.

Air enters the mouth or nose and travels through the windpipe, bronchi and bronchioles to the alveoli. The exchange of oxygen and carbon dioxide happens in the alveoli.

  • The alveoli absorb oxygen from the air and pass it into the blood, which circulates the oxygen around the body.
  • Carbon dioxide, which is a waste product of the body’s cells, passes from the blood into the alveoli and is breathed out.
  • The lungs produce a mixture of fats and proteins called lung or pulmonary surfactant. The surfactant coats the surfaces of the alveoli, making it easier for them to expand and deflate with each breath.

The lungs also help protect the body from harmful substances in the air, such as smoke, pollution, bacteria and viruses. These substances can pass through the nose and become trapped in the lungs. The lungs produce a thick, slippery fluid (mucus), which can trap and partly destroy these substances from the air. The cilia move rapidly to push the mucus up through the bronchi, where it is removed by coughing or swallowing.

respiratory system

The group of organs and tissues that are involved in breathing.

The respiratory system includes the nose, mouth, sinuses around the nose (called the paranasal sinuses), pharynx, larynx (voice box), trachea (windpipe), bronchi and lungs. It also includes the respiratory muscles, which are the muscles that help you breathe (such as the diaphragm).

mediastinum

The space in the chest between the lungs, breastbone and spine that contains the heart, great blood vessels, thymus, trachea (windpipe), esophagus and lymph nodes.

lymphatic system

The group of tissues and organs that produce and store cells that fight infection and diseases.

The lymphatic system includes the adenoids, tonsils, spleen, thymus, lymph nodes, lymph vessels and bone marrow.

Also called the lymph system.

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Great progress has been made

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Some cancers, such as thyroid and testicular, have survival rates of over 90%. Other cancers, such as pancreatic, brain and esophageal, continue to have very low survival rates.

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