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The kidneys are part of the urinary system. There are 2 kidneys in the body, one on either side of the spine under the lower ribs, deep inside the upper part of the abdomen. The ureters are thin tubes that connect each kidney to the bladder. They are about 25 to 30 cm (10 to 12 in) long. The urethra is a small tube that connects the bladder to the outside of the body. There is an adrenal gland just above each kidney. The adrenal glands are part of the endocrine system.
The kidneys are bean-shaped organs. An adult kidney is about 10 cm (4 in) long, 6 cm (2 to 3 in) wide and 3 cm (1 to 2 in) thick. A layer of fatty tissue holds the kidneys in place against the muscle at the back of the abdomen.
Gerota’s fascia is a thin, fibrous tissue on the outside of the kidney. Below Gerota’s fascia is a layer of fat.
The renal capsule is a layer of fibrous tissue that surrounds the body of the kidney inside the layer of fat.
The cortex is the tissue just under the renal capsule.
The medulla is the inner part of the kidney.
The renal pelvis is a hollow area in the centre of each kidney where urine (pee) collects.
The renal artery brings blood to the kidney.
The renal vein takes blood back to the body after it has passed through the kidney.
The renal hilum is the area where the renal artery, renal vein and ureter enter the kidney.
The nephrons are the millions of small tubes inside each kidney. Each nephron has 2 parts. Tubules are tiny tubes that collect the waste materials and chemicals from the blood moving through the kidney. The corpuscles contain a clump of tiny blood vessels called glomeruli that filter the blood as it moves through the kidney. The waste products are passed through the tubules to the collecting ducts, which drain into the renal pelvis.
What the kidneys do
The main function of the kidneys is to filter water, impurities and wastes from the blood.
The blood from the body enters the kidneys through the renal arteries. Once in the kidney, the blood passes through the nephrons, where waste products and extra water are removed. The clean blood is returned to the body through the renal veins.
The waste products filtered from the blood are then concentrated into urine. The urine is collected in the renal pelvis. The ureters move the urine to the bladder, where it is stored. Urine is passed out of the bladder and the body through the urethra.
The kidneys also act as endocrine glands. They make these hormones:
- Erythropoietin (EPO) stimulates the bone marrow to make red blood cells.
- Calcitriol, a form of vitamin D, helps the colon absorb calcium from the diet.
- Renin helps control blood pressure.
The group of glands and cells in the body that make and release hormones (which control many functions such as growth, reproduction, sleep, hunger and metabolism) into the blood.
The endocrine system is made up of the hypothalamus, pituitary gland, pineal gland, thyroid, parathyroid gland, adrenal gland, pancreatic islet cells (also known as islets of Langerhans) and the ovaries or testicles.
A substance that regulates specific body functions, such as metabolism, growth and reproduction.
Natural hormones are produced by glands. Artificial or synthetic hormones can be made in the lab.
A mineral that the body uses to build and maintain bones, teeth and connective tissues (tissue that surrounds and supports various organs in the body), and is essential in metabolism and the functioning of nerves and muscles.
Calcium is found in dairy products, leafy green vegetables, seeds and nuts, tofu and dried fruit.
Calcium is a type of electrolyte.
Great progress has been made
Some cancers, such as thyroid and testicular, have survival rates of over 90%. Other cancers, such as pancreatic, brain and esophageal, continue to have very low survival rates.