Make an impact in your community by donating or registering for Relay For Life.
Prognosis and survival for childhood Hodgkin lymphoma
Children with Hodgkin lymphoma (HL) and their parents may have questions about prognosis and survival. Prognosis and survival depend on many factors. Only a doctor familiar with a child’s health history, type of cancer, stage, characteristics of the cancer, treatments chosen and response to treatment can put all of this information together with survival statistics to arrive at a prognosis.
A prognosis is the doctor’s best estimate of how cancer will affect a child and how it will respond to treatment. A prognostic factor is an aspect of the cancer or a characteristic of the child that the doctor will consider when making a prognosis. A predictive factor influences how a cancer will respond to a certain treatment. Prognostic and predictive factors are often discussed together and they both play a part in deciding on a treatment plan and a prognosis.
The following are prognostic factors for childhood HL.
The earlier the stage, the more favourable the prognosis. Children with an advanced stage of disease (stage 3 or 4) have a poorer prognosis.
Tumour bulk refers to the size of the cancer. A bulky tumour is a large tumour in a lymph node, group of lymph nodes or organ. Tumour bulk is considered a negative prognostic factor. This means that the larger the tumour, the less favourable the prognosis.
Presence of B symptoms
Children who have B symptoms at the time of diagnosis generally have a poorer prognosis. B symptoms are a fever over 38°C, drenching night sweats and unexplained weight loss.
Response to treatment
Children who respond quickly to the first chemotherapy treatments tend to have a better prognosis.
Reducing the burden of cancer
Canadians can help CCS fund the best research and support people living with cancer by donating and volunteering.