October 2013 Innovation Grants results

We are pleased to announce the results of the most recent Innovation Grants competition to support unique and creative research ideas that will impact cancer. Below is a listing of newly awarded Canadian Cancer Society (CCS) Innovation Grants.

Out of a total of 214 grant applications, 46 Canadian Cancer Society Innovation Grants have been approved – a 21% success rate. All grants have been awarded to a maximum budget of $200,000 with a maximum 3 year term. The 46 grants total almost $9 million in funding over the terms of these grants. This number is substantially higher than anticipated due to the strength of the submissions in this round, as a result additional funds were allocated.

We are also very pleased that all grants are being funded to their full panel recommended amounts and that no administrative decrements are being applied.

Funds committed to this competition have been made possible by the significant efforts of Canadian Cancer Society volunteers and donors across the country.

Summaries of awarded grants

Please note:
  • Amounts listed below represent the total dollars awarded by grant year and may include funds for salaries, supplies, and/or equipment.
  • The start date for these grants is February 1, 2014.

  • Only the Principal Investigator is named in this listing. Co-Principal Investigators, Co-Applicants and/or Additional Authors may also be associated with these grants.

Note Carefully:

Although every effort has been made to ensure the accuracy of the listing below, this list does not constitute an "official" notification.

Successful applicants will be informed, in writing, with an official Notification of Award giving the details pertaining to their grant.

Applicant
Institution
Title
Award
Abraham, Ninan
University of British Columbia
Therapeutic targeting of the IL-7Ra pathway in acute lymphoblastic leukemia
2014/2015 :  $66,668
2015/2016 :  $66,666
2016/2017 :  $66,666
Bally, Marcel
BC Cancer Agency (Vancouver)
Lipid-based nanoparticulate formulations of copper complexed diethyl-dithiocarbamate used alone and in combination with temozolomide and/or Irinophore C to treat glioblastoma multiforma
2014/2015 :  $100,000
2015/2016 :  $100,000
Batada, Nizar
Ontario Institute for Cancer Research
DNA repair associated mutational signatures as biomarkers
2014/2015 :  $98,650
2015/2016 :  $100,000
Blank, Volker
Lady Davis Institute
Novel regulatory pathways controlling hematopoietic stem cell fate
2014/2015 :  $100,000
2015/2016 :  $91,810
Boutros, Paul
Ontario Institute for Cancer Research
Genomic characterization of Rb1+/+ retinoblastoma
2014/2015 :  $100,000
2015/2016 :  $100,000
Buckstein, Rena
Sunnybrook Research Institute
The screening for MDS mutations in the aging population for early detection of disease
2014/2015 :  $94,650
2015/2016 :  $97,590
Cypel, Marcelo
The Toronto Hospital (General Division) - UHN
Development of isolated lung perfusion for the treatment of cancer metastases to the lungs
2014/2015 :  $100,000
2015/2016 :  $96,830
Dedhar, Shoukat
BC Cancer Agency (Vancouver)
Identification and development of novel anti-cancer agents targeting centrosome clustering
2014/2015 :  $93,112
2015/2016 :  $93,112
Diorio, Caroline
Laval University
DNA methylation in normal breast tissue associated to risk of second contralateral breast cancer
2014/2015 :  $100,000
2015/2016 :  $99,896
Dirks, Peter
Hospital for Sick Children
Wnt signalling control of glioblastoma stem cell fate
2014/2015 :  $99,715
2015/2016 :  $98,563
Fradet, Vincent
Laval University
Phase II double-blind randomized controlled trial of concentrated omega-3 (mainly EPA) before prostatectomy evaluating the effects on prostate cancer proliferation, inflammation and quality of life.
2014/2015 :  $32,600
2015/2016 :  $97,145
2016/2017 :  $70,250
Gallouzi, Imed
McGill University
Role of stress granules in preventing cancer-induced muscle wasting
2014/2015 :  $98,537
2015/2016 :  $98,537
Girardin, Stephen
University of Toronto
The role of NLRX1 in colorectal cancer and apoptosis
2014/2015 :  $95,000
2015/2016 :  $95,000
Gotay, Carolyn
University of British Columbia
Increasing healthy outcomes for prostate cancer survivors: an innovative cooking class intervention feasibility study
2014/2015 :  $73,328
2015/2016 :  $85,907
Harkness, Troy
University of Saskatchewan
Metformin and microarrays: an innovative approach to treating and monitoring drug resistant canine lymphoma
2014/2015 :  $78,832
2015/2016 :  $86,168
Jones, Russell
McGill University
Investigating the role of the immune system in the pathology of LKB1-mediated tumourigenesis
2014/2015 :  $62,435
2015/2016 :  $63,435
2016/2017 :  $66,435
Jones, Steven
BC Cancer Agency (Vancouver)
Modulators of FBXL2 to induce degradation of oncogenes – an innovative therapeutic approach
2014/2015 :  $97,620
2015/2016 :  $97,620
Joshua, Anthony
Ontario Cancer Institute/PMCC - UHN
The utility and relevance of exome sequence analysis and circulating tumour DNA in assessing tumour heterogeneity in BRAF mutant melanoma
2014/2015 :  $62,005
2015/2016 :  $90,695
2016/2017 :  $46,980
Kelley, Shana
University of Toronto
An integrated fluidic chip for exosome analysis
2014/2015 :  $100,000
2015/2016 :  $100,000
Kerbel, Robert
Sunnybrook Research Institute
A strategy for developing models of spontaneous bone metastasis in mice
2014/2015 :  $89,000
2015/2016 :  $89,000
Khokha, Rama
Ontario Cancer Institute/PMCC - UHN
Proteome analysis of the mammary epithelial hierarchy: normal and high-risk
2014/2015 :  $94,900
2015/2016 :  $94,900
Kramer, Desre
Cancer Care Ontario
From awareness to behavioural change (A2B): exploring the impact of heightened awareness of workplace exposures in Sarnia and Sudbury
2014/2015 :  $97,768
2015/2016 :  $99,065
Kung, Sam K.P.
University of Manitoba
A novel role of GM-CSF in evading immune surveillance of natural killer cells in breast cancer
2014/2015 :  $67,239
2015/2016 :  $68,315
2016/2017 :  $64,329
Lam, Wan
BC Cancer Research Centre
Development of organ specific immunomodulators for the treatment of lung cancer
2014/2015 :  $100,000
2015/2016 :  $100,000
Mai, Sabine
University of Manitoba
Nuclear architecture in cancer
2014/2015 :  $99,999
2015/2016 :  $98,211
Makrigiannis, Andrew
University of Ottawa
Innate immunosurveillance of breast cancer
2014/2015 :  $92,707
2015/2016 :  $92,707
Mazroui, Rachid
Laval University
Role of heme-regulated kinase in chemoresistance
2014/2015 :  $78,000
2015/2016 :  $78,000
Muller, William
McGill University
Targeting canonical Wnt/ß-catenin signalling in ErbB2 mammary tumour progression
2014/2015 :  $97,500
2015/2016 :  $97,500
Nelson, Brad
BC Cancer Agency (Victoria)
How does the immune system contend with intratumoral heterogeneity?
2014/2015 :  $97,938
2015/2016 :  $100,000
Nitz, Mark
University of Toronto
Mass cytometry probes to evaluate tumour hypoxia
2014/2015 :  $99,750
2015/2016 :  $99,750
Park, Morag
McGill University
Gastric cancer, mechanisms for intervention
2014/2015 :  $100,000
2015/2016 :  $100,000
Pause, Arnim
McGill University
Investigation of tumour suppressive mechanism of ESCRT-dependent receptor degradation
2014/2015 :  $100,000
2015/2016 :  $100,000
Petrecca, Kevin
McGill University
Development of novel therapeutics to prevent brain cancer invasion
2014/2015 :  $86,500
2015/2016 :  $84,000
Prive, Gilbert
Ontario Cancer Institute/PMCC - UHN
The function of LZTR-1 in glioblastoma
2014/2015 :  $61,667
2015/2016 :  $63,255
2016/2017 :  $64,831
Ruth, Thomas
BC Cancer Research Centre
Targeted alpha therapy with At-211
2014/2015 :  $96,966
2015/2016 :  $100,000
Sabiston, Catherine
University of Toronto
Connecting peers in motion: a dyadic lifestyle activity intervention for women diagnosed with cancer
2014/2015 :  $96,201
2015/2016 :  $71,536
2016/2017 :  $23,668
Shah, Sohrab
University of British Columbia
Building a bridge from the cancer genome to the cancer clinic with visual analytics
2014/2015 :  $99,663
2015/2016 :  $100,000
Sinnett, Daniel
Hopital Sainte-Justine
Long noncoding RNAs deregulated in childhood acute lymphoblastic leukemia
2014/2015 :  $99,678
2015/2016 :  $99,499
Steidl, Christian
BC Cancer Research Centre
Detection of genomic rearrangements in archival lymphoma tissues using targeted capture sequencing
2014/2015 :  $100,000
2015/2016 :  $99,351
Tepass, Ulrich
University of Toronto
A new model to study the cell biology of epithelial to mesenchymal transition (EMT)
2014/2015 :  $69,500
2015/2016 :  $64,500
2016/2017 :  $64,500
Thomson, Axel
McGill University
Mediators of stromal androgen response in prostate cancer as new therapeutic interventions
2014/2015 :  $44,000
2015/2016 :  $47,000
2016/2017 :  $44,500
Trudel, Suzanne
Ontario Cancer Institute/PMCC - UHN
A companion study to a phase II clinical trial of sequential treatment with MEK followed by AKT inhibition for the treatment of relapsed multiple myeloma
2014/2015 :  $70,573
2015/2016 :  $70,573
2016/2017 :  $58,573
Veillette, Andre
IRCM - Institut de Recherches Cliniques de Montréal
Mouse models to understand mechanisms of action and toxicity of elotuzumab, a new treatment for multiple myeloma
2014/2015 :  $66,666
2015/2016 :  $66,666
2016/2017 :  $66,668
Watson, Peter
BC Cancer Research Centre
Inflammation and resistance to endocrine therapy in breast cancer
2014/2015 :  $96,708
2015/2016 :  $96,708
Weber, Michael
The Research Institute of the McGill University Health Centre (RI-MUHC)
Bone scaffolds as delivery systems for local and controlled release of anti-resorptive in bone metastasis treatment
2014/2015 :  $99,745
2015/2016 :  $99,965
Young, Edmond
University of Toronto
Accessible microfluidic technology for modeling breast cancer tumor microenvironments
2014/2015 :  $83,800
2015/2016 :  $58,100
2016/2017 :  $58,100

Last modified on: July 22, 2015