April 2013 Innovation Grants results

We are pleased to announce the results of the most recent Innovation Grants competition to support unique and creative research ideas that will impact cancer. Below is a listing of newly awarded Canadian Cancer Society (CCS) Innovation Grants.

Out of a total of 159 grant applications, 37 Canadian Cancer Society Innovation Grants have been approved – a 23% success rate. All grants have been awarded to a maximum budget of $200,000 with a maximum 3 year term. The 37 grants total over $7.2 million in funding over the terms of these grants. As a result of the high quality of applications, additional funds were allocated to support greater than the 15-20 grants originally budgeted for this competition. We would also like to acknowledge the Lotte & John Hecht Memorial Foundation and the Rowe Estate who supported specific grants in this competition as indicated below.

We are also very pleased that all grants are being funded to their full panel recommended amounts and that no administrative decrements are being applied. Funds committed to this competition have been made possible by the significant efforts of Canadian Cancer Society volunteers and donors across the country.

Summaries of awarded grants

Please note:
  • Amounts listed below represent the total dollars awarded by grant year and may include funds for salaries, supplies, and/or equipment.
  • The start date for these grants is August 1, 2013.
  • Only the Principal Investigator is named in this listing. Co-Principal Investigators, Co-Applicants and/or Additional Authors may also be associated with these grants.
Note Carefully:

Although every effort has been made to ensure the accuracy of the listing below, this list does not constitute an "official" notification.

Successful applicants will be informed, in writing, with an official Notification of Award giving the details pertaining to their grant.

Applicant
Institution
Title
Award
Alibhai, Shabbir
The Toronto Hospital (General Division) - UHN
A phase II RCT of strategies to reduce fractures and improve bone health in men on ADT
2013/2014 :  $98,965
2014/2015 :  $99,221
Basik, Mark
Jewish General Hospital
The role of carcinoma-associated fibroblasts in drug resistance in breast cancer
*Partial funds provided by the Hecht Memorial Foundation
2013/2014 :  $100,000
2014/2015 :  $100,000
Campbell, Kristin
University of British Columbia
The impact of lifestyle on the breast tissue environment
2013/2014 :  $57,625
2014/2015 :  $55,624
2015/2016 :  $86,751
Cheung, Peter
York University
Discovering cancer-epigenome readers using the novel technique BICON
2013/2014 :  $100,000
2014/2015 :  $100,000
Egan, Sean
Hospital for Sick Children
Development of a mouse model for Magi3-Akt3 fusion gene positive breast cancer
2013/2014 :  $100,000
2014/2015 :  $100,000
Ferbeyre, Gerardo
University of Montreal
Nucleolar protein degradation in oncogene-induced senescence
2013/2014 :  $100,000
2014/2015 :  $100,000
Fortin, Marc-André
Laval University
Palladium-gold particles for prostate cancer brachytherapy
2013/2014 :  $97,970
2014/2015 :  $100,000
Foulkes, William
Lady Davis Institute
DICER1 and pituitary blastoma: Keys to understanding pituitary development and tumorigenesis
2013/2014 :  $100,000
2014/2015 :  $100,000
Gagnon, Etienne
University of Montreal
Defects in zinc homeostasis in TILs: a novel target for improving T cell-based immunotherapies
*Funds provided by the Hecht Memorial Foundation
2013/2014 :  $66,000
2014/2015 :  $65,000
2015/2016 :  $69,000
Gingras, Anne-Claude
Mount Sinai Hospital
Studying modulated cancer interactomes: an integrated computational and experimental pipeline
2013/2014 :  $100,000
2014/2015 :  $100,000
Hoare, Todd
McMaster University
Novel physically-targeted "smart" nanoparticles for tumour treatment
*Funds provided by the Hecht Memorial Foundation
2013/2014 :  $91,500
2014/2015 :  $94,450
Junop, Murray
McMaster University
Identification of SNM1A inhibitors with adjuvant anticancer activity
2013/2014 :  $100,000
2014/2015 :  $62,500
Kolios, Michael
Ryerson University
Detecting circulating tumour cells using photoacoustic ultrasound RF spectroscopy
*Partial funds provided by the Hecht Memorial Foundation
2013/2014 :  $99,780
2014/2015 :  $69,130
Krajinovic, Maja
Hopital Sainte-Justine
MicroDNA - novel source of genetic variability - role in shaping individual sensitivity to cancer treatment
2013/2014 :  $98,792
2014/2015 :  $98,297
Lapointe, Rejean
Centre de recherche du CHUM - Pav. Notre-Dame
Genome-wide transcriptional analysis of intra-tumoural T cell subsets
2013/2014 :  $82,080
2014/2015 :  $84,665
2015/2016 :  $33,255
Larijani, Mani
Memorial University of Newfoundland
Understanding structure-function relationships in activation-induced cytidine deaminase (AID) in order to design inhibitors for treatment of lymphoma and leukemia
*Funds provided by the Estate of W. Gary Rowe
2013/2014 :  $60,666
2014/2015 :  $68,666
2015/2016 :  $70,666
Lecuyer, Eric
IRCM - Institut de Recherches Cliniques de Montréal
Epithelial cell polarity regulation by localized mRNAs
2013/2014 :  $100,000
2014/2015 :  $100,000
Li, Shawn (Shun-Cheng)
University of Western Ontario
Harnessing numb lysine methylation for targeted cancer therapy
2013/2014 :  $80,000
2014/2015 :  $90,000
Mager, Dixie
BC Cancer Agency (Vancouver)
Aberrant gene regulation in colon cancer: role of transposable elements
2013/2014 :  $100,000
2014/2015 :  $100,000
Martin, Alberto
University of Toronto
Assessing the role of gut microbial derived metabolites in colon cancer
*Funds provided by the Hecht Memorial Foundation
2013/2014 :  $100,000
2014/2015 :  $100,000
McBride, Heidi
Montreal Neurological Institute
Characterization of a novel mitochondrial tumour suppressor
2013/2014 :  $99,728
2014/2015 :  $99,728
Metrakos, Peter
The Research Institute of the McGill University Health Centre (RI-MUHC)
Integrated molecular histology and imaging mass spectrometry of lipid signatures: application to human colorectal cancer liver metastasis
2013/2014 :  $100,000
2014/2015 :  $96,000
Moorehead, Roger
University of Guelph
The function of Akt isoforms in lung cancer
2013/2014 :  $66,583
2014/2015 :  $66,583
2015/2016 :  $66,583
Naus, Christian
University of British Columbia
Modification of glioma microenvironment by direct cell-to-cell transfer of microRNA mediated by the gap junction protein Cx43
2013/2014 :  $56,500
2014/2015 :  $60,700
2015/2016 :  $66,055
Puts, Maria (Martine)
University of Toronto
What is the role of comorbidity, frailty and functional status in the decision-making process for older adults with cancer and their family members, cancer specialist, and family physician?
2013/2014 :  $46,747
2014/2015 :  $27,975
Robbins, Stephen
University of Calgary
A novel approach to targeting organ-selective metastasis
2013/2014 :  $100,000
2014/2015 :  $100,000
Sabri, Siham
McGill University
Novel role of the O6-methylguanine-DNA methyltransferase (MGMT) in glioblastoma angiogenesis and invasion: Biological and clinical significance
2013/2014 :  $100,000
2014/2015 :  $100,000
Stagljar, Igor
University of Toronto
Elucidation of EGFR signalling pathways in non-small cell lung cancer (NSCLC) using a novel interactive proteomics approach
2013/2014 :  $100,000
2014/2015 :  $100,000
Suh, Woong-Kyung
IRCM - Institut de Recherches Cliniques de Montréal
Regulation of immunoediting and anticancer immunity by an immunoinhibitory protein B7-H4
2013/2014 :  $85,368
2014/2015 :  $85,368
Truong, Kevin
University of Toronto
Reprogramming cells to target tumour cells
2013/2014 :  $90,831
2014/2015 :  $90,831
Ursini-Siegel, Josie
Lady Davis Institute
Molecular mechanisms governing breast cancer immunosuppression
2013/2014 :  $59,500
2014/2015 :  $69,500
2015/2016 :  $69,500
Woo, Minna
The Toronto Hospital (General Division) - UHN
Dissecting the inflammatory and growth signalling in hepatocellular carcinoma (HCC) pathogenesis
2013/2014 :  $66,971
2014/2015 :  $65,893
2015/2016 :  $67,136
Wu, Xiao Yu (Shirley)
University of Toronto
Improving tumour response to radiation therapy by modulating the tumour microenvironment using novel bioreactive nanoparticles
2013/2014 :  $95,500
2014/2015 :  $95,500
Zemp, Roger
University of Alberta
Development and application of genetically-encoded photoacoustic biosensors for imaging of tumour biology
2013/2014 :  $100,000
2014/2015 :  $100,000
Zhang, Li
The Toronto Hospital (General Division) - UHN
Enhancing immunotherapy by conjugation of porphysome nanoparticles to immune cells
2013/2014 :  $94,031
2014/2015 :  $94,031
Zhang, Zhaolei
University of Toronto
Investigating regulatory roles of pseudogenes and other non-coding RNAs in cancer
2013/2014 :  $98,500
2014/2015 :  $100,000
Zuniga-Pflucker, Juan Carlos
Sunnybrook Research Institute
DL4-VLR for simplified human T cell regeneration strategies
2013/2014 :  $100,000
2014/2015 :  $100,000

Last modified on: October 28, 2013