Genetic risk of aggressive stomach cancer
An aggressive form of stomach cancer is more common in Newfoundland families. By studying nearly 4,000 people from 75 families, Dr David Huntsman at the BC Cancer Agency in Vancouver determined that those with mutations in the CDH1 gene have a high chance of developing this stomach cancer – a 70% chance for men and a 56% chance for women. If people in this high-risk group are closely monitored, stomach cancers may be detected earlier and treated more effectively.
Reference: JAMA Oncology, April 2015