A wire localization biopsy is a procedure that uses a fine wire to mark the exact location of a lump or abnormality. It is done before a surgeon performs an excisional biopsy to remove the lump. This procedure may also be called wire localization, fine-wire localization or needle localization.
Wire localization biopsy is most commonly used to locate lumps or abnormalities in the breast, though it may be used for other parts of the body as well. It is used to:
The first part of a wire localization biopsy is done in the x-ray department of a hospital.
The second part of a wire localization biopsy is done in the operating room.
Biopsy samples are sent to the pathology lab. A pathologist (a doctor who specializes in the causes and nature of disease) will look at the cells in the tissue to see if they contain cancer. The pathology report indicates the characteristics and type of cells present and if cells are normal, non-cancerous or cancerous.
The doctor will decide whether further tests, procedures or treatment are needed.
A clinical trial led by the Society’s NCIC Clinical Trials group found that men with prostate cancer who are treated with intermittent courses of hormone therapy live as long as those receiving continuous therapy.