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Vaginal cancer

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Treatment of stage IV vaginal carcinoma

The following are treatment options for stage IV vaginal carcinoma. The types of treatments given are based on the unique needs of the person with cancer. Treatment is the same for stage IV squamous cell carcinoma and adenocarcinoma.

Treatment of stage IVA vaginal carcinoma

Radiation therapy is the primary treatment for stage IVA vaginal carcinoma. Treatment may include both brachytherapy and external beam radiation therapy, with or without surgery.

Treatment of stage IVB vaginal carcinoma

Radiation therapy is the primary treatment for stage IVB vaginal carcinoma for relief of symptoms and to improve quality of life. Radiation may be given with or without chemotherapy.

The chemotherapy drugs that may be used are:

  • 5-fluorouracil (5-FU, Adrucil)
  • cisplatin (Platinol AQ)
  • mitomycin (Mutamycin)
  • methotrexate
  • cyclophosphamide (Cytoxan, Procytox)
  • bleomycin (Blenoxane)
  • paclitaxel (Taxol)
  • docetaxel (Taxotere)

Clinical trials

Women with vaginal carcinoma may be offered the opportunity to participate in clinical trials. For more information, go to clinical trials.


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