The following are treatment options for stage IV stomach cancer. Your healthcare team will suggest treatments based on your needs and work with you to develop a treatment plan.
Chemotherapy is a main treatment for stage IV stomach cancer to slow the growth of the cancer. Chemotherapy for stomach cancer may be given as a single drug or as a combination of 2 or more drugs. Sometimes radiation therapy is given over the same time period as chemotherapy (this is called chemoradiation). The most common chemotherapy options for stage IV stomach cancer are:
Some examples of chemotherapy regimens (a combination of 2 or more drugs) used for stage IV stomach cancer are:
Trastuzumab (Herceptin) and ramucirumab (Cyramza) are targeted therapy drugs used to treat stage IV stomach cancer. Trastuzumab (Herceptin) may be offered for stage IV stomach cancer that is HER2-positive.
Targeted therapy is usually given until the cancer no longer responds to treatment, grows larger or spreads.
Surgery is sometimes offered for stage IV stomach cancer to relieve the symptoms of advanced cancer such as bleeding, blockage or pain.
Some people who are well enough to have surgery may have part of the stomach removed that contains the tumour.
A stent is a hollow metal or plastic tube. Stents may be used if a tumour is blocking the opening of the stomach near the esophagus. It will allow a person with advanced stomach cancer to swallow more easily.
If surgery or other methods cannot relieve a blockage caused by a stomach tumour, a person with advanced stomach cancer may have a feeding tube placed through a surgical opening in the abdomen. A feeding tube is used to give the person liquid nutrition to help maintain their weight.
A bowel obstruction is when the small intestine or colon is partly or completely blocked. The blockage prevents food, fluids and gas from passing through the intestines normally. If you have a bowel obstruction, you may need surgery to remove or bypass the part of the intestine that is blocked.
External beam radiation therapy may be offered for stage IV stomach cancer. It is used alone or in combination with chemotherapy (called chemoradiation). It may be used to relieve the symptoms caused by advanced stomach cancer such as uncontrolled bleeding, pain, trouble swallowing (dysphagia) or a blockage.
You may want to consider a type of care to make you feel better rather than treat the cancer itself. This may be because the cancer treatments don’t work anymore, they’re not likely to improve your condition or they may cause side effects that are hard to cope with. There may also be other reasons why you can’t have or don’t want cancer treatment.
Talk to your healthcare team. They can help you choose care and treatment for advanced cancer.
You may be asked if you want to join a clinical trial for stomach cancer. Find out more about clinical trials.
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The Canadian Cancer Society provides helpful information about government income programs, financial resources and other resources available to families struggling to make sense of the personal financial burden they face.