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Precancerous conditions of the stomach are changes to stomach cells that make them more likely to develop into cancer. These conditions are not yet cancer. But if they aren’t treated, there is a chance that these abnormal changes may become stomach cancer.
Gastric epithelial dysplasia occurs when the cells of the stomach lining (called the mucosa) change and become abnormal. These abnormal cells may eventually become adenocarcinoma, the most common type of stomach cancer.
Gastric epithelial dysplasia can be divided into 2 types:
The following risk factors increase your chance of developing gastric epithelial dysplasia:
Each of these conditions causes changes in the stomach lining that can lead to the development of abnormal cells and dysplasia.
Gastric epithelial dysplasia does not cause any signs or symptoms.
Gastric epithelial dysplasia is often found during stomach tests, such as an upper gastrointestinal endoscopy, done for other health reasons. Tests used to diagnose gastric epithelial dysplasia may include:
Treatment options for gastric epithelial dysplasia will depend on the grade of dysplasia.
Surgery is not usually needed to treat low-grade dysplasia. The doctor will closely monitor you and do an upper gastrointestinal endoscopy and a biopsy once a year.
Treatment for high-grade dysplasia may include:
Gastric adenoma (adenomatous gastric polyp) is a type of polyp made up of abnormal (atypical) glandular cells from the stomach lining. They are found in areas of the stomach where the normal tissue has been changed by chronic inflammation. If left untreated, a gastric adenoma could develop into adenocarcinoma, the most common type of stomach cancer.
Gastric adenoma is usually found in the antrum of the stomach. It may grow as a slightly elevated area on the lining of the stomach (sessile) or outward from the surface with a head and stalk (pedunculated). A gastric adenoma usually measures less than 2 cm in size. Gastric adenomas are more likely to become cancerous if they:
The following risk factors increase your chance of developing gastric adenoma:
Small gastric adenomas do not cause any signs or symptoms. Signs and symptoms may appear if the gastric adenoma grows larger and causes a blockage (obstruction) in the stomach. They may include:
If you have symptoms or your doctor thinks you might have gastric adenoma, you will be sent for tests. Tests used to diagnose gastric adenoma may include:
Treatment options for gastric adenoma include:
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