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Diagnosing rhabdomyosarcoma usually begins with a visit to your child’s doctor. The doctor will ask you about any symptoms your child has and do a physical exam. Based on this information, the doctor may refer you to a specialist or order tests to check for rhabdomyosarcoma or other health problems.
The process of diagnosis may seem long and frustrating. It’s normal to worry, but try to remember that other health conditions can cause similar symptoms as rhabdomyosarcoma. It’s important for the healthcare team to rule out other reasons for a health problem before making a diagnosis of rhabdomyosarcoma.
The following tests are commonly used to diagnose or rule out rhabdomyosarcoma. Many of the same tests used to diagnose cancer are used to find out the stage, which is how far the cancer has progressed. The doctor may also order other tests to check the child’s general health and to help plan treatment.
A health history is a record of the symptoms, risk factors and all the medical events and problems your child has had in the past. In taking a health history, the doctor will ask questions about a personal or family history of certain genetic conditions, including:
A physical exam allows the doctor to look for any signs of rhabdomyosarcoma. The doctor will do a physical exam and:
Find out more about physical exam.
A CBC measures the number and quality of white blood cells, red blood cells and platelets. A CBC is done to check if the cancer has spread to the bone marrow. It is also used as a baseline that doctors can check against during treatment.
Find out more about complete blood count (CBC).
Blood chemistry tests measure certain chemicals in the blood. They show how well certain organs are functioning and can help find abnormalities. Blood chemistry tests can also be used as a baseline that doctors can check against during treatment.
Find out more about blood chemistry tests.
An x-ray uses small doses of radiation to make an image of the body’s structures on film. A chest x-ray is sometimes done to see if cancer has spread to the lungs. If a CT scan of the chest is done, doctors won’t do a chest x-ray as well.
Find out more about x-ray.
A computed tomography (CT) scan uses special x-ray equipment to make 3-D and cross-sectional images of organs, tissues, bones and blood vessels inside the body. A computer turns the images into detailed pictures.
Doctors use a CT scan for tumours in the thorax, abdomen, pelvis and the space between the peritoneumperitoneumThe membrane that lines the walls of the abdomen and pelvis (parietal peritoneum), and covers and supports most of the abdominal organs (visceral peritoneum). and the abdominal wall (called the retroperitoneum). It is used to:
Find out more about CT scan.
Magnetic resonance imaging (MRI) uses powerful magnetic forces and radiofrequency waves to make cross-sectional images of organs, tissues, bones and blood vessels. A computer turns the images into 3-D pictures.
Doctors use an MRI for tumours in the head and neck, arms, legs or pelvis. It is used to:
Find out more about MRI.
An ultrasound uses high-frequency sound waves to make images of structures in the body. It is used to look at the kidneys and structures around them. Doctors may also use ultrasound to look at tumours in the pelvis, including in the bladder, prostate, testicles, gallbladder, bile ducts and kidneys.
Find out more about ultrasound.
A bone scan uses bone-seeking radioactive materials (called radiopharmaceuticals) and a computer to create a picture of the bones. It is used to see if the cancer has spread to the bones.
Find out more about bone scan.
A positron emission tomography (PET) scan uses radioactive materials called radiopharmaceuticals to look for changes in the metabolic activity of body tissues. A computer analyzes the radioactive patterns and makes 3-D colour images of the area being scanned.
A PET scan may be used to:
A PET scan can be combined with low-resolution CT scans (called PET-CT scan). Newer machines can do PET and CT scans at the same time. PET-CT scan is used to examine the metabolic activity of specific areas in the body.
PET scans may not be available in all cancer treatment centres. Find out more about PET scan.
During a biopsy, the doctor removes tissues or cells from the body so they can be tested in a lab. The report from the lab will confirm whether or not cancer cells are present in the sample.
A biopsy is the only way to make a definite diagnosis of rhabdomyosarcoma. It is usually done after a CT or MRI of the tumour.
The most common type of biopsy done is a surgical, or open, biopsy. During a surgical biopsy, the doctor cuts through the skin and removes a piece of the tumour. The doctor may also remove lymph nodes near the tumour to see if cancer has spread to them. The child is asleep under general anesthesia during the biopsy.
Find out more about surgical biopsy.
If doctors can’t do a surgical biopsy, they may do a needle biopsy. There are 2 types of needle biopsies:
Core needle biopsy uses a needle to remove a small sample of the tumour. If the tumour is deep within the body, the doctor may use ultrasound or CT scan to guide the needle into the tumour. Find out more about core needle biopsy.
Fine needle aspiration (FNA) biopsy uses a thin needle and a syringe to remove a small amount of fluid or cells. FNA works best with tumours that are just under the skin and can be easily reached with the needle. Find out more about FNA.
Bone marrow aspiration and biopsy removes tissues or cells from the bone marrow so they can be tested in a lab. Doctors use bone marrow aspiration and biopsy to see if cancer has spread to the bone marrow.
Find out more about bone marrow aspiration and biopsy.
A lumbar puncture, or spinal tap, removes a small amount of cerebrospinal fluid (CSF) from the spine. CSF is the fluid that surrounds and helps protect the brain and spinal cord. The CSF fluid removed during a lumbar puncture is examined under a microscope to see if cancer has spread to the central nervous system (CNS). A lumbar puncture may be done if the tumour is near the tissue surrounding the brain and spinal cord (called the meninges).
Find out more about lumbar puncture.
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The Canadian Cancer Society is actively lobbying the federal government to establish a national caregivers strategy to ensure there is more financial support for this important group of people.