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The following are treatment options for stage IV prostate cancer. The types of treatments given are based on the unique needs of the person with cancer.
Hormonal therapy is the primary treatment for stage IV prostate cancer. Up to 85% of men with advanced prostate cancer will respond to hormonal therapy.
The types of hormonal therapy are:
Radiation therapy may be offered for stage IV prostate cancer:
External beam radiation therapy is not given for 4–6 weeks after a transurethral resection of the prostate (TURP), to reduce the risk of scarring in the urethra (urethral stricture).
TURP may be offered for stage IV prostate cancer. This surgery relieves the urinary symptoms caused by the prostate tumour.
Biological therapy may be offered for stage IV prostate cancer. The type of biological therapy that may be given to men with stage IV prostate cancer is denosumab (Xgeva).
Denosumab may be used:
Bisphosphonates can be used for prostate cancer that has spread to the bone to relieve bone pain or prevent fractures in men with advanced castrate-resistant prostate cancer. The bisphosphonate used is zoledronic acid (Zometa).
Men with prostate cancer may be offered the opportunity to participate in clinical trials. For more information, go to clinical trials.