Canadian Cancer Society logo

Prostate cancer

You are here: 

Biological therapy for prostate cancer

Biological therapy may be used to reduce the risk of bone-related events in prostate cancer. It is also called biotherapy or biological response modifiers (BRMs).

Biological therapy uses natural or manufactured substances to kill, control or change the behaviour of cancer cells. Different types of biological therapies work in different ways.

Biological therapy may be used:

  • to strengthen bone and prevent osteoporosis due to hormonal therapy
  • reduce the risk of bone complications due to metastatic prostate cancer

Drugs, doses and schedules vary from person to person.

Biological therapy drugs

RANK-ligand inhibitor is a biological therapy in which a monoclonal antibody blocks the action of RANK ligand - a protein that promotes bone resorption. This helps to strengthen bone.

The most common biological therapy drug used to treat prostate cancer is:

  • denosumab(Xgeva)

For more detailed information on specific drugs, go to sources of drug information.

See a list of questions to ask your doctor about biological therapy.


Dr Lillian Sung Improving supportive care for children with cancer

Read more

A home away from home

Illustration of house

For cancer patients who must travel a great distance to get to treatment, Canadian Cancer Society lodges offer a welcoming place to stay.

Learn more