Canadian Cancer Society logo

Prostate cancer

You are here: 

Biological therapy for prostate cancer

Biological therapy may be used to reduce the risk of bone-related events in prostate cancer. It is also called biotherapy or biological response modifiers (BRMs).

Biological therapy uses natural or manufactured substances to kill, control or change the behaviour of cancer cells. Different types of biological therapies work in different ways.

Biological therapy may be used:

  • to strengthen bone and prevent osteoporosis due to hormonal therapy
  • reduce the risk of bone complications due to metastatic prostate cancer

Drugs, doses and schedules vary from person to person.

Biological therapy drugs

RANK-ligand inhibitor is a biological therapy in which a monoclonal antibody blocks the action of RANK ligand - a protein that promotes bone resorption. This helps to strengthen bone.

The most common biological therapy drug used to treat prostate cancer is:

  • denosumab(Xgeva)

For more detailed information on specific drugs, go to sources of drug information.

See a list of questions to ask your doctor about biological therapy.

Stories

Dr Mohammad Akbari Dr Mohammad Akbari pinpointed a new breast cancer susceptibility gene.

Learn more

Clinical trial discovery improves quality of life

Illustration of test tubes

A clinical trial led by the Society’s NCIC Clinical Trials group found that men with prostate cancer who are treated with intermittent courses of hormone therapy live as long as those receiving continuous therapy.

Learn more