Canadian Cancer Society logo

Parathyroid cancer

You are here: 

Signs and symptoms of parathyroid cancer

A sign is something that can be observed and recognized by a doctor or healthcare professional (for example, a rash). A symptom is something that only the person experiencing it can feel and know (for example, pain or tiredness). The signs and symptoms of parathyroid cancer can also be caused by other health conditions. It is important to have any unusual symptoms checked by a doctor.

The signs and symptoms of parathyroid cancer are caused by a parathyroid gland tumour secreting too much parathyroid hormone (PTH). This condition is called hyperparathyroidism. Too much PTH causes hypercalcemia (increased calcium levels in the blood).

Signs and symptoms of parathyroid cancer are mainly caused by hypercalcemia and include:

  • fatigue
  • muscle weakness
  • increased thirst
  • urinary problems
    • need to urinate more often (frequency)
    • excessive amount of urine (polyuria)
  • bone pain
  • poor appetite
  • nausea
  • vomiting
  • weight loss
  • dehydration
  • constipation
  • trouble thinking clearly
  • bone fractures
  • lump in the neck that can be felt
  • change in the voice (such as hoarseness)
  • trouble swallowing
  • kidney problems
    • kidney stones
    • kidney disease
  • stomach ulcer
  • inflammation of the pancreas


Dr Artem Cherkasov Research could lead to better cancer treatments with fewer side effects.

Read more

Funding lifesaving clinical trials

Illustration of science instruments

The Canadian Cancer Society is funding lifesaving clinical trials that give people with cancer access to the newest types of treatment.

Learn more