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Stages of neuroendocrine cancer

Staging is a way of describing or classifying a cancer based on the extent of cancer in the body. The most common staging system for neuroendocrine cancer is the TNM system. The International Union Against Cancer (UICC) uses the TNM system to describe the extent of many solid tumour cancers.

The TNM staging for neuroendocrine cancer varies according to the site of origin and the type of tumour. TNM staging proposals for neuroendocrine cancer at each site are still being finalized and there is no widely accepted international standard.


TNM stands for tumour, nodes, metastasis. TNM staging describes:

  • the size of the primary tumour
  • the number and location of any regional lymph nodes that have cancer cells in them
  • whether the cancer has spread or metastasized to another part of the body

Recurrent neuroendocrine cancer

Recurrent neuroendocrine cancer means that the cancer has come back after it has been treated. It may recur in the same location as the original cancer or it may recur in another part of the body (metastatic neuroendocrine cancer).


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