Treatments for stage 2 nasopharyngeal cancer

The following are treatment options for stage 2 nasopharyngeal cancer. Your healthcare team will suggest treatments based on your needs and work with you to develop a treatment plan.

Chemoradiation

Chemoradiation is the main treatment for stage 2 nasopharyngeal cancer. In chemoradiation, chemotherapy is given during the same time period as radiation therapy. Each treatment makes the other more effective.

Chemoradiation therapy for stage 2 nasopharyngeal cancer uses cisplatin and external radiation therapy.

Radiation therapy

You may be offered radiation therapy for stage 2 nasopharyngeal cancer if you can’t tolerate chemoradiation and its side effects. External radiation is given to the site of the tumour followed by preventive radiation to the lymph nodes in the neck (cervical lymph nodes).

The type of external radiation therapy used for stage 2 nasopharyngeal cancer is usually intensity-modulated radiation therapy (IMRT).

Chemotherapy

Chemotherapy with cisplatin and fluorouracil (also called 5-fluorouracil or 5-FU) is often given after radiation or chemoradiation therapy to lower the chance that the cancer will come back (recur).

Clinical trials

Talk to your doctor about clinical trials open to people with nasopharyngeal cancer in Canada. Clinical trials look at new ways to prevent, find and treat cancer. Find out more about clinical trials.

Expert review and references

  • Guideline Resource Unit (GURU). Nasopharyngeal Cancer Treatment. Version 2 ed. Edmonton: Alberta Health Services; 2021: Clinical Practice Guideline HN-003. https://www.albertahealthservices.ca/info/cancerguidelines.aspx.
  • Bossi P, Chan AT, Licitra L, Trama A, Orlandi A, et al. Nasopharyngeal carcinoma:ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology. 2021: 32(4) 452-465.
  • American Cancer Society. Treating Nasopharyngeal Cancer. 2022.

Medical disclaimer

The information that the Canadian Cancer Society provides does not replace your relationship with your doctor. The information is for your general use, so be sure to talk to a qualified healthcare professional before making medical decisions or if you have questions about your health.

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