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The cervix is part of the female reproductive system. The female reproductive system is made up of internal organs, including the vagina, uterus, ovaries and fallopian tubes. It is also made up of the external genital organs, including the parts that make up the vulva (the clitoris, vaginal lips and the opening to the vagina). All the internal organs are located in the pelvis, which is the lower part of the abdomen between the hip bones.
The cervix is the lower, narrow part of a women’s uterus, or womb. The cervix connects the main body of the uterus to the vagina, or birth canal.
The cervix is about 2 cm (1 in) long. It is made up mostly of connective tissue and muscle. It is divided into 2 main parts:
The endocervical canal is the passageway from the uterus to the vagina.
The 2 main types of cells in the cervix are:
The squamous cells join the columnar cells in an area of the cervix called the squamo-columnar junction. This is also called the transformation zone because the tall columnar cells are constantly being changed into flat squamous cells, especially during puberty and child-bearing years. Precancerous changes of the cervix and most cervical cancers start in the transformation zone.
The cervix connects the body of the uterus to the vagina. Part of the lining of the cervix contains glands that make and release mucus. For most of the menstrual cycle and during pregnancy, the mucus is thick and stops sperm from entering the uterus. The thick mucus also helps to protect the uterus and the upper female reproductive organs from harmful bacteria.
When a mature egg is released from an ovary each month (called ovulation), the mucus changes and becomes thinner. The thinner mucus allows sperm to pass through the cervix into the uterus.
Every month, except during pregnancy or when a woman is in menopause, the lining of the uterus (called the endometrium) is shed through the cervix into the vagina, then out of the body. This process is called menstruation.
During childbirth, the cervix widens, or dilates, allowing the baby to pass through the birth canal.
A clinical trial led by the Society’s NCIC Clinical Trials group found that men with prostate cancer who are treated with intermittent courses of hormone therapy live as long as those receiving continuous therapy.